Roche to discuss approach to improving therapeutic index of ADCs

Top Quote SMi reports : Principal Scientist from Roche to speak on ADC development at the 5th ADC Summit in London. End Quote
  • (1888PressRelease) March 07, 2016 - London UK : With the FDA's recent approval of ADCs Adcetris and Kadcyla, the industry has reached a tipping point now that it has entered the commercial stage. New innovations in developing the next best generation ADCs are bursting into the clinic at a rapid rate.

    Ben Fillippo Krippendorff, Principal Scientist at Roche, will be speaking at SMi's 5th ADC Summit in London taking place in London on 23-24 May 2016. Krippendorff will be speaking on Day 2 of the conference about predicting tissue distribution and clearance of antibody formats to improve selectivity of targeted therapies.

    His presentation will cover:
    Estimating the tissue distribution of antibodies and antibody fragments based on plasma pharmacokinetics
    Estimation of ADC distribution and tissue specific clearances that influence the therapeutic window
    Optimising biotherapeutic modalities with optimal biodistribution properties to targe (and avoid) specific tissues

    For more information on speakers and their topics, visit the event website at An Early Bird discount of 200 applies to all online bookings made by 31 March.

    The 5th ADC Summit will bring together leading industry professionals to explore the various innovations in approaches and technologies for the development of next generation ADCs. Event attendees will hear the latest insights from Takeda on Adcetris; discuss the latest advancements in research and development from Medimmune; and analyse case studies from big pharma companies such as Roche, Bayer, Pfizer, AstraZeneca, Novartis and many more.

    For tailored sponsorship and branding opportunities contact Alia Malick on +44 (0) 20 7827 6168 or email: amalick ( @ ) smi-online dot co dot uk dot For group/delegate bookings contact Fateja Begum on +44 (0) 20 7827 6184 or email fbegum ( @ ) smi-online dot co dot uk dot For media enquiries contact Honey de Gracia on +44 (0) 20 7827 6102 or email hdegracia ( @ ) smi-online dot co dot uk dot

    5th ADC Summit
    23-24 May 2016
    London, UK
    Contact e-mail: hdegracia ( @ ) smi-online dot co dot uk
    Contact number: +44 (0) 207 827 6102
    Event Website:

    About SMi Group:
    Established since 1993, the SMi Group is a global event-production company that specializes in Business-to-Business Conferences, Workshops, Masterclasses and online Communities. We create and deliver events in the Defence, Security, Energy, Utilities, Finance and Pharmaceutical industries. We pride ourselves on having access to the world's most forward thinking opinion leaders and visionaries, allowing us to bring our communities together to Learn, Engage, Share and Network. More information can be found at

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