Barry Morgan, VP at GSK to Speak at 8th Modern Drug Summit Oct 24-26, 2012 in Philadelphia, PA

Top Quote Barry Morgan, Vice President of Molecular Discovery Research at GlaxoSmithKline will give a plenary keynote presentation on "DNA Encoded Libraries - A Disruptive Innovation for Molecular Discovery?" at the 8th Modern Drug Discovery & Development Summit taking place on October 24-26, 2012 in Philadelphia, PA End Quote
  • (1888PressRelease) September 24, 2012 - Barry Morgan, Vice President of Molecular Discovery Research at GlaxoSmithKline will give a plenary keynote presentation on "DNA Encoded Libraries - A Disruptive Innovation for Molecular Discovery?" at the 8th Modern Drug Discovery & Development Summit taking place on October 24-26, 2012 in Philadelphia, PA

    Encoded Library Technology (ELT) is a novel approach to molecular discovery based upon the creation of large encoded libraries of novel, drug-like structures that can be rapidly interrogated to identify families of compounds with affinity for a macromolecular target. ELT Libraries are constructed by sequential "split and pool" cycles that alternate organic synthesis with enzymatic oligonucleotide ligation: in this way GSK has been able to assemble a library pool containing over 30 billion (3x10^10) structures. In his presentation, Dr. Morgan will describe studies with these libraries against a variety of drug targets, yielding families of "hit" molecules that inhibit the function of these targets with single digit nanomolar potency.

    Barry A. Morgan, Ph.D. is Vice President, Molecular Discovery Research, and Site Head at GlaxoSmithKline, Boston. He was previously Senior Vice President for Chemistry and Discovery Sciences at PRAECIS Pharmaceuticals, where he was one of the inventors of the Encoded Library Technology platform. PRAECIS was acquired by GSK in February 2007. Prior to joining PRAECIS in 2001, he was Director of Chemistry at Biomeasure, a Boston-based subsidiary of IPSEN from 1993 to 2001. From 1980 to 1993, he was at Sterling Winthrop holding several positions in Medicinal and Combinatorial Chemistry, and Drug Discovery. He has authored over 100 publications and is an inventor of more than 30 patents in the area of drug discovery.

    GTC's 8th Modern Drug Discovery and Development Summit features a plenary keynote session followed by five parallel tracks:
    9th Stem Cell Research and Therapeutics Conference
    7th Assay and Drug Discovery Technologies Conference
    4th Translational Medicine Conference
    3rd Pharmacokinetics and Pharmacodynamics Conference
    Biotechnology Transfer and Commercialization Conference

    For more information, please visit www.gtcbio.com

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