Synthon chooses Avacta's Optim 1000 for high throughput formulation studies

Top Quote Pharmaceutical developers at Synthon, a global specialist in the development and manufacture of generic medicines, have chosen an Optim 1000 high throughput, micro-volume protein analysis system from Avacta for preliminary formulation studies. End Quote
  • (1888PressRelease) April 16, 2013 - Bas Kokke, Principal Scientist at Synthon, explained: "In recent years, our work has begun to focus on biopharmaceuticals and for that we needed different instrumentation to develop assays and study proteins in far more detail. After initial discussions with Avacta, we sent some samples for analysis and were impressed by the Company's approach and responsiveness. As well as high throughput, a big advantage of the Optim 1000 is the small sample volume required - down to 9 µl - which is perfect for us. This is so important because we don't want to make large quantities of each formulation when conducting fairly large, high throughput studies early on in a project."

    Guy de Roo, Lead Scientist at Synthon, added: "The Optim 1000 is now used for all formulation projects as an initial screening instrument and we regularly perform around 50 formulations for a given project, where we used to be restricted to 10 or 15. The melting point data from the Optim system has shown a good correlation with long term stability, and this is very valuable to us. The support we have had from Avacta has been excellent; they are very open and flexible and our work has really progressed."

    For more information, visit www.avactaanalytical.com

    About Avacta Analytical
    Avacta Analytical provides services and innovative instrumentation to the biopharmaceutical market. Our focus is to equip customers with a broad range of capabilities, enabling them to develop their therapeutics quicker, cheaper and better.

    The ground-breaking Optim 1000 instrument combines, for the first time, the powerful analytical capabilities of fluorescence and static light scattering technologies to provide an exciting new technique.

    Our services business specialises in supporting characterisation, formulation, comparability and stability studies of therapeutic proteins. We are able to draw upon a wide range of analytical capabilities and aim to give our customers a flexible value-added service.

    Avacta Analytical is an ISO 9001 2008 registered company.

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