Pfizer to give a keynote address on reviving covalent drug design in oncology at SMi's 15th annual event this February

Top Quote SMi group reports: Doug Johnson, Research Fellow at Pfizer will be giving a keynote address on Day 1 at the SMi's 15th annual Advances and Progress in Drug Design conference (15-16 February 2016, Holiday Inn Kensington Forum, London) on: Reviving covalent drug design: Discovery of PF-04457845, an irreversible FAAH inhibitor with exquisite selectivity. End Quote
  • (1888PressRelease) January 26, 2016 - His presentations topics will include:
    • The unique benefits of small molecule covalent drug candidates
    • Activity-based protein profiling and clickable probes to evaluate selectivity of covalent binding
    • Biomarkers and PET ligand to determine target engagement in humans

    With the recent industry updates, this year's Advances and Progress in Drug Design event will focus on enabling biophysical tools and highlight key advancements in protein-based drug discovery. It will take a closer look at combined HTS and FBDD methods for lead generation and the application of biophysical methods such as: X-Ray Crystallography, NMR, biocore and ITC to aid the prioritization of target inhibitors.

    Plus, two interactive half-day post-conference workshops:
    - A fresh view on molecular recognition: the dynamic perspective - presented by Barcelona University
    - Analysis and Application of Ligand Conformation in Drug Design - presented by C4X Discovery

    Key speakers in 2016 include:
    • Gregg Seigal, Chief Executive Officer, ZoBio
    • Doug Johnson, Research Fellow, Pfizer
    • Tove Sjφgren, Associate Director, AstraZeneca
    • Jordi Munoz-Muriedas, Investigator, GSK
    • Herman van Vlijmen, Senior Director, Janssen
    • Armin Ruf, Section Head, Biostructure, Roche
    • Manuel Francisco Molina-Martin, Research Scientist, Eli Lilly, and many more

    For the full event agenda/ to register please visit: www.drug-design.co.uk

    Alternatively, get in touch with Matthew Apps: +44 20 7827 6093 or e-mail: mapps ( @ ) smi-online dot co dot uk
    Those who are interested in attending are advised to register now to avoid disappointment.

    About SMi Group:
    Established since 1993, the SMi Group is a global event-production company that specializes in Business-to-Business Conferences, Workshops, Masterclasses and online Communities. We create and deliver events in the Defence, Security, Energy, Utilities, Finance and Pharmaceutical industries. We pride ourselves on having access to the world's most forward thinking opinion leaders and visionaries, allowing us to bring our communities together to Learn, Engage, Share and Network. More information can be found at http://www.smi-online.co.uk

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