OZ Biosciences introduces the viro-MICST reagent: the next generation of transduction tools

Top Quote Viro-MICST™ reagent is specially designed for i-MICST Technology. This reagent is a new magnetic nanoparticles formulation issued from our Magnetofection ™ Technology that allows high transduction efficiency with low Multiplicity of Infection (MOI) during magnetic cell separation. End Quote
  • (1888PressRelease) April 05, 2012 - OZ Biosciences SAS, specialized in the development of innovative transfection technologies, launches Viro-MICST™ into its successful line of specialty reagents for transduction.

    Ideal for sensitive cell types such as primary and stem cells, the Viro-MICST™ reagent allows the efficient and specific transduction of target cells directly on magnetic cell-purification columns.

    Designed for i-MICST™ Technology (Integrated Magnetic Immuno-Cell Sorting and Transduction/Transfection), Viro-MICST™ leads to an increase in the transduction efficiency with low-titer virus preparations compared to regular transduction methods.

    "We continuously improve our core technology", explains Olivier Zelphati, CEO of OZ Biosciences. "Indeed, Viro-MICST™ is a new specific magnetic nanoparticle formulation evolved from our Magnetofection™ Technology. In combination with MACS® technology* Viro-MICST™ ensures high transduction efficiency with low Multiplicity of Infection (MOI) during simultaneous magnetic cell separation."

    Viro-MICST™ binds to viruses. As both magnetically labeled target cells and virus-Viro-MICST™ complexes are retained by the magnetic field into the column, the viruses can interact and infect target cells with high efficiency.
    Viro-MICST™ was developed in association with MACS® technology* from Miltenyi Biotec.

    Magnetofection™ is a simple and highly efficient viral and non-viral gene delivery method (in vitro and in vivo). This magnetic assisted transfection is based on the use of magnetic nanoparticles associated to the gene vectors. In this way, the magnetic force allows a rapid concentration of genetic material onto cells and promotes cellular uptake.

    About OZ Biosciences:
    OZ Biosciences creates, develops and produces innovative transfection reagents and transduction tools for the scientific community and pharmaceutical industry. As an innovative technology-based company, OZ Biosciences continually provides enabling technologies for the delivery of biomolecules. Located in the Luminy Scientific Park, the heart of important biological research activity in Marseille, France, the company has established a strong position in the field of molecular delivery systems.

    For more information please visit www.ozbiosciences.com

    Contact: Olivier Zelphati - +33(0)4 86 94 85 16 - contact ( @ ) ozbiosciences dot com

    SOURCE: OZ Biosciences

    Note to editors

    MACS® is a registered trademark owned by Miltenyi Biotec GmbH and the use of MACS® column is proprietary and patented technology. For any further licensed of MACS® system, please contact Miltenyi.

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