Breakthrough Prostate Cancer Animal Study Presented at International Oncology Conference
Results of a new study show that the oral administration of a doctor-designed formula produce a statistically significant suppression of tumor growth, compared to controls.
- (1888PressRelease) October 15, 2011 - New animal study confirms the dramatic effects of a natural formula against aggressive prostate cancer tumors. Researchers at the Methodist Research Institute at Indiana University conducted the study on mice, using a human prostate cancer xenograft model (outlined below). These latest results have been presented to hundreds of researchers and medical doctors in Rhodes, Greece during the 16th World Congress on Advances in Oncology and 14th International Symposium on Molecular Medicine.
Lead investigator, Dr. Daniel Sliva presented the results of this in vivo (live animal) study, demonstrating the significant effects of the formula in suppressing the proliferation and metastasis of human hormone refractory (androgen independent) prostate cancer cells. In addition, the toxicology analysis proved that this formula is non-toxic and poses no risk of side effects. "Dietary supplements are used as an alternative or adjuvant therapies. However, rigorous scientific verification of their biological activity in vitro and in vivo is necessary for the acceptance of dietary supplements in conventional cancer treatment and prevention," says Dr. Sliva.
This in vivo study is significant because hormone refractory prostate cancer (androgen independent) is especially hard to treat. It's the more aggressive, advanced form of prostate cancer that often leads to metastasis and progression of the cancer.
Formulated with Natural Ingredients Proven to Support Prostate
The all-natural, doctor-designed formula combines botanical extracts, phytonutrients, botanically enhanced medicinal mushrooms, and antioxidants. Ingredients were selected based on scientific research demonstrating their abilities to fight prostate abnormalities and provide broad spectrum prostate support.
Formula Inhibits Tumor Growth and Genes Related to Metastasis
Results of the study show that the oral administration of this formula produced a statistically significant suppression of tumor growth, compared to controls. The study was performed using a xenograft model of human prostate cancer in mice. A xenograft model is when tissue or organs from an individual of one species are transplanted or grafted onto an organism of another species, genus, or family. So human prostate cancer cells (tissue) are grafted onto a laboratory animal, which in this case were mice.
In addition to a significant reduction in tumor volume, results of this study showed the formula also worked to inhibit a number of genes involved in cancer proliferation and metastasis. Two interesting genes that were suppressed relate to the metastatic potential and can point out to the ability of this preparation to not only inhibit the primary tumor growth, but also the metastatic process, an even more important benefit in the fight against aggressive prostate cancer.
Study Further Validates Previous In-Vitro Results
This formula has previously been studied at research laboratories at Columbia University, NY, NY and at the Cancer Research Laboratory, Methodist Research Institute, Indiana University Health, Indianapolis, IN, using in vitro methods (i.e. cell culture studies) and gene expression analysis. These prior studies showed significant results in this formula's ability to inhibit prostate cancer growth and proliferation.
This present study is a milestone in the research of this formula, because it used a laboratory animal model to test for toxicity and showed how the formula suppressed human prostate cancer tumor growth within a living mammal.
"In summary, this dietary supplement is a natural compound for the possible therapy of human hormone refractory (independent) prostate cancer," says Dr. Sliva. Ongoing research on this formula in prostate cancer models continues to show encouraging results, and additional studies are forthcoming.
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