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11
May
2009

Actelion provides update on BUILD-3 study in Idiopathic Pulmonary Fibrosis

Actelion Ltd (SIX: ATLN) today announced that the Independent Data and Safety Monitoring Board (DSMB) has recommended continuation of the pivotal Phase III study BUILD-3, evaluating the efficacy and safety of bosentan (Tracleer®) in patients suffering from idiopathic pulmonary fibrosis.


(1888PressRelease) May 11, 2009 - The DSMB was mandated to perform an efficacy and futility interim analysis of 75% of events in BUILD-3 to assess whether study continuation is warranted based on the primary objective of demonstrating delayed disease worsening or death.

Final study results are expected before the end of 2009.

Actelion Ltd

Actelion Ltd is a biopharmaceutical company with its corporate headquarters in Allschwil/Basel, Switzerland. Actelion's first drug Tracleer®, an orally available dual endothelin receptor antagonist, has been approved as a therapy for pulmonary arterial hypertension. Actelion markets Tracleer® through its own subsidiaries in key markets worldwide, including the United States (based in South San Francisco), the European Union, Japan, Canada, Australia and Switzerland. Actelion, founded in late 1997, is a leading player in innovative science related to the endothelium - the single layer of cells separating every blood vessel from the blood stream. Actelion's over 2000 employees focus on the discovery, development and marketing of innovative drugs for significant unmet medical needs. Actelion shares are traded on the SIX Swiss Exchange (ticker symbol: ATLN) as part of the Swiss blue-chip index SMI (Swiss Market Index SMI® )

For further information please contact:

Roland Haefeli
Vice President, Head of Investor Relations & Public Affairs
Actelion Pharmaceuticals Ltd, Gewerbestrasse 16, CH-4123 Allschwil
+41 61 565 62 62
+1 650 624 69 36
http://www.actelion.com

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Contact Information

Roland Haefeli

Financial News

Voice: +41 61 565 62 62

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